Deep within the Amazon, a mysterious and deadly predator rises again. When a billionaire expedition led by a ruthless treasure hunter invades the jungle in search of an ancient serpent crown, they awaken the legendary queen of the anacondas — a massive, intelligent, and territorial beast.

Dr. Elena Vasquez, a fearless herpetologist, is forced to join the mission to protect the balance of nature. As her team ventures deeper, they uncover ruins guarded by the queen serpent herself — larger, faster, and deadlier than ever. One by one, they fall prey to the jungle’s wrath.

With time running out and trust eroding among survivors, Elena must make a stand not only against the giant predator but against human greed that threatens to doom them all. The jungle doesn’t forgive — and the Queen doesn’t forget.